Quiz  /  Bioinformatics Gate & PSU MCQ Questions With Answers

  • 1. 
    People in this career field use computers and technology to gain a new understanding of biology (living things).

  • Healthcare
  • Biomanufacturing
  • Genetics and Bioscience
  • Bioinformatics

  • 2. 
    If I am looking at the same gene or protein in different species, I am looking at

  • ortholog[ue]s
  • homolog[ue]s
  • paralog[ue]s
  • catalog[ue]s

  • 3. 
    Among the following which one is not the approach to the local alignment?

  • Smith-Waterman algorithm
  • K-tuple method
  • Words method
  • Needleman-Wunsch algorithm

  • 4. 
    Which of the following would be an example of gene therapy technology?

  • development of a nasal spray that contains copies of the normal gene that is defective in person with cystic fibrosis
  • cutting DNA into fragments with restriction enzymes
  • modifying E. coli to produce indigo dye for coloring denim blue jeans
  • separation DNA fragments using gel electrophoresis

  • 5. 
    Blast uses

  • feng doolittle
  • heuristic algorithm
  • dynamic
  • progressive

  • 6. 
    Which of the following does not describe local alignment?

  • A local alignment aligns a substring of the query sequence to a substring of the target sequence
  • A local alignment is defined by maximizing the alignment score, so that deleting a column from either end would reduce the score, and adding further columns at either end would also reduce the score
  • Local alignments have terminal gaps
  • The substrings to be examined may be all of one or both sequences; if all of both are included then the local alignment is also global

  • 7. 
    Which sequence of DNA bases would pair with this partial strandATG TGA CAG

  • ATG TGA CAG
  • TAC ACT GTC
  • GTA AGT GAC
  • CAT TCA CTG

  • 8. 
    CD command

  • move from one directory to another
  • current directory

  • 9. 
    Full form of PIR?

  • Protein information Report
  • Protein Information Result
  • Protein information resource
  • Protein Information Record

  • 10. 
    Following interactions are responsible for folding of aprotein into a teritiary structure

  • Ionic interactions
  • VanderWalls interactions
  • Hydrogen Bonds
  • All the above

  • 11. 
    EMBOSS

  • European Molecular Biology Open Software Suite
  • European Molecular Biology Open source site

  • 12. 
    What are the nucleotides made of?

  • Sugar, Phosphate, nitrogen base
  • Phosphate, Adenine, nitrogen base
  • Thymine, Adenine, Cytomine
  • Phosphate, Nitrogen, Adenine

  • 13. 
    UniProt stores

  • Curated and predicted proteins
  • Predicted proteins only
  • Curated proteins only
  • Protein functions only

  • 14. 
    The study of all of an organism's proteins, including its identity, structure, interaction, and abundance

  • proteomics
  • bioethics
  • bioinformatics
  • Human Genome Project

  • 15. 
    Which of the following best describes a DNA molecule?

  • double helix
  • contains ribose
  • made of amino acids
  • contains Uracil

  • 16. 
    Chromosomal rearrangements due to insertion sequences have apparently contributed to the evolution of several human pathogens.

  • TRUE
  • FALSE

  • 17. 
    Horizontal gene transfer

  • is rare and only occurs between closely related strains
  • is common and may sometimes occur between unrelated organisms
  • does not provide an advantage to organisms
  • only occurs in prokaryotes

  • 18. 
    What do you mean by bioinformatics?

  • biotechnology with computers
  • biotech +IT=Chemistry +stats +PHY
  • Biology on IT
  • Biology

  • 19. 
    Fullform of PERL

  • Peas Extract Remember Language
  • Practical Extraction and Report Language

  • 20. 
    The central hub for the collection of functional information on proteins with accurate consistent and rich annotation.

  • Genbank
  • Uniprot
  • NCBI
  • Wikipedia

  • 21. 
    Local alignments are more used when _____________

  • There are totally similar and equal length sequences
  • Dissimilar sequences are suspected to contain regions of similarity
  • Similar sequence motif with larger sequence context
  • Partially similar, different length and conserved region containing sequences

  • 22. 
    Fragments of DNA have been extracted from the remnants of extinct woolly mammoths, amplified, and sequenced. These can now be used to

  • understand the evolutionary relationships among members of related species.
  • appreciate the reasons why mammoths went extinct.
  • study the relationships among woolly mammoths and other wool-producers.
  • clone live woolly mammoths.

  • 23. 
    A technique that places a gene into a cell to correct a hereditary disease or to improve the genome

  • bioinformatics
  • cloning by nuclear transfer
  • single nucleotide polymorphism (SNP)
  • gene therapy

  • 24. 
    Which of the following interactions is responsible for formation of a secondary structure in a protein

  • Disulphide bond
  • Electrostatic interaction
  • Hydrogen bond
  • peptide bond

  • 25. 
    The NCBI RefSeq database

  • contains sequences of wildtype and mutated genes
  • only sequences of wildtype genes
  • only sequences of mutated genes

  • 26. 
    Informatics in Bioinformatics can perform

  • Data Management
  • Data Computation
  • Data Mining
  • All of these

  • 27. 
    It is the transfer of genetic material for the purpose of treating human disease.

  • chemotherapy
  • gene therapy
  • gene transfer
  • gene editing
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