Quiz  /  Immunology Gate & PSU MCQ Questions With Answers

  • 1. 
    Conditions required for successful activation of T helper

  • Presence of signal 0
  • Presence of inadequate amount of CD28
  • Formation of microclusters of TCR complex in T helper
  • All of above

  • 2. 
    DNP is

  • A hapten
  • An Adjuvant
  • A flocculant
  • None of the above

  • 3. 
    Autocrine signalling happens during ------------------- of T helper cells

  • MHC II binding with TCR
  • Synthesis of CD28
  • Differentiation of T helper
  • None of the above

  • 4. 
    The CD4 is present as part of -------------- in T lymphocytes

  • CD28 R
  • TCR complex
  • Microcomplex
  • ILR complex

  • 5. 
    The T helper releases a ------------------- during autocrine signalling

  • IL-2
  • IL-3
  • IL-1
  • IL-R

  • 6. 
    A 5-year-old child falls and scratches herself and within a few days has an enlarged lymph node in the area draining the abrasion. The cells in the lymph node are reacting to the foreign stimulus that entered the skin and that was transported to the lymph node by which of the following?

  • immunoglobulin
  • T cells
  • Dendritic cells
  • TLRs

  • 7. 
    Which of the following cells would NOT be found in a germinal center in a lymph node?

  • dendritic cells
  • B lymphocytes
  • plasma cells
  • monocytes

  • 8. 
    The signal helping in verification of the presented Antigen as self or non self

  • Signal 0
  • Signal 1
  • Signal 2
  • Signal 3

  • 9. 
    Peyer's patches are found in

  • Bone marrow
  • Thymus
  • SALT
  • MALT

  • 10. 
    The cells which provide signals to B cells for complete activation

  • T regulatory
  • T cytotoxic
  • T helper
  • All of the above

  • 11. 
    Variable region of antibodies are located on

  • Fc portion
  • Constant region
  • Fab portion
  • Light chains only

  • 12. 
    Castles intrinsic factor

  • Absorption of vitamin B12
  • Deficiency leads to Anemia
  • Produced by Parietal cells of stomach
  • All of above

  • 13. 
    An epitope is located on

  • Antibody
  • Antigen
  • Both antibody and antigen
  • None of these

  • 14. 
    Which of the following is a distinction between the innate and adaptive immune systems?

  • the ability of the cells of only one system to produce cytokines.
  • the capacity for exquisite antigenic specificity in only one system
  • the capacity of only one system to recognize virally infected cells.
  • the ability of cells of only one system to mediate cell cytotoxicity

  • 15. 
    Lymph nodes and spleen have germinal centers in which B cells respond to antigen and produce antibodies. A function unique to the spleen w.r.t. other peripheral lymphoid organs is

  • filtration of blood-borne pathogens.
  • production of dendritic cells.
  • production of red blood cells.
  • antigen presentation

  • 16. 
    Signal II leads to anergy or inactivation of T helper when

  • Inadequate quantity of CD28 is expressed
  • The APC is presenting an autoantigen
  • Competitive binding of CTLA 4 with CD80 or CD86
  • All of above

  • 17. 
    Examples for professional APCs

  • B lymphocytes
  • Dendritic cells
  • Erythrocytes
  • Both A & B

  • 18. 
    A T lymphocyte which has not encountered an antigen yet

  • Novice
  • Small
  • Stem
  • Naive

  • 19. 
    Agglutination reaction is seen in

  • Blood grouping
  • Gel precipitation
  • Soluble antigens
  • All of the options

  • 20. 
    BSA can act as

  • A hapten
  • A carrier protein
  • An antibody
  • A flocculant

  • 21. 
    An adjuvant

  • Can reduce the antigenicity of a substance
  • Can enhance the autoimmunity in Females
  • Can increase the antigenicity of a substance
  • All of the options
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